Medical Services to Support, Restore, and Enhance
Hair Restoration with Hyper PRP™
A program that combines Hyper PRP and microneedling to help support fuller, healthier looking hair
Shown to increase hair density for many men and women with androgenetic alopecia
Autologous (derived from patient’s own blood). Standards-based preparation. Clinician-directed care. Some uses are investigational. Results are NOT guaranteed. Individual results and patient experiences may vary significantly.
Hair Restoration with Hyper PRP™ + Microneedling
A standards-based Growth Factor Therapy™ (GFT) approach designed for motivated adults with androgenetic alopecia
Carefully prepared from your own blood with Calibrated Centrifugation™, Hyper PRP may help support scalp health and hair density when applied by a licensed clinician after professional microneedling. Results vary by person and protocol. Some combinations are still being studied. [1–2]
Connect with a Hyper PRP provider near you.
Quick transparency
READ THIS FIRST
Leading reviews and randomized trials report that platelet rich plasma (PRP) can increase hair density for many people with androgenetic alopecia, especially over the first three to six months. Effects on hair thickness are more mixed. Study protocols and PRP formulations differ, so results do too. Your licensed clinician will place Hyper PRP within a broader plan and track progress over time. [1–3]
Regulatory Note for the United States
Hyper PRP is prepared from a small blood sample using Calibrated Centrifugation™ within a standards-based Growth Factor Therapy™ (GFT) framework. In the United States, certain devices are FDA-cleared to prepare PRP at the point of care. However, PRP injections or scalp applications for hair loss are not FDA-approved for this indication. Many device summaries also state that PRP "has not been evaluated for any clinical indications" and is not indicated for delivery to the circulatory system. Licensed clinicians align care with device labeling, clinical judgment, and patient preferences. [14–15]
Who this service may help
Hair Restoration with Hyper PRP delivered via microneedling is intended for adults with androgenetic alopecia (male and female pattern hair loss) who want a non-surgical option that can live beside first line therapies. Early research suggests PRP can increase hair density for some people. This medical service does not create new follicles, and it will not stop genetic hair loss on its own. Many licensed clinicians combine PRP with topical minoxidil or home light therapy to support results. Your medical history, goals, and scalp exam guide the plan. Results vary by person and protocol. [1–2,6,10]
If you already use minoxidil or other therapies, share that with your Hyper PRP provider so the plan is tailored.
Evidence snapshot and transparency
Across randomized trials and pooled reviews:
Hair density. Many studies show higher hair counts after PRP compared with placebo; the size of the effect varies across trials. [1–2,4–5]
Hair thickness. Signals are mixed. Several pooled analyses and trials do not show a consistent diameter increase across all studies. [1–2]
Combination care. A 2024 systematic review suggests PRP plus minoxidil may outperform minoxidil alone for some patients, though the evidence is low quality and heterogeneous. [3]
Safety. When delivered by trained clinicians, reported side effects are usually mild and short-term, such as redness, tenderness, swelling, or small bruises. Serious complications are uncommon but possible. [1–2,4]
Bottom line. PRP has been studied for pattern hair loss and may help some people—especially when combined with evidence-based basics. Protocols differ, and outcomes vary. Licensed clinicians track results so progress is visible and meaningful for each person. [1–3]
How Hair Restoration with Hyper PRP works
Platelet rich plasma (PRP). PRP is a concentrate of your own platelets, which carry signaling proteins and growth factors that participate in repair and support microcirculation. Microneedling uses fine, medical-grade needles to create precise micro-channels in the scalp. This micro-injury can trigger a gentle healing response and improve topical delivery across the skin barrier. [7–8]
Within the GFT standards. A Hyper PRP provider draws a small blood sample, uses Calibrated Centrifugation to prepare Hyper PRP, and applies it to the scalp with professional microneedling in a protocol-based workflow. The goal is a consistent dose and composition of PRP, while recognizing that outcomes still vary by person.
What happens in the tissue? Signals in PRP have been linked to support for dermal papilla cells, new capillary formation, and pathways such as Wnt and beta-catenin that govern hair cycling. Microneedling can activate similar pathways and may enhance penetration of topical medicines like minoxidil. These are biologic goals; confirmation of the exact human mechanism is ongoing. [7–9]
Geek out on this
For the science curious
Hair follicles rotate through growth (anagen), regression (catagen), and rest (telogen). In androgenetic alopecia, follicles gradually miniaturize and spend less time in growth. Growth factors in PRP—such as vascular endothelial growth factor and platelet derived growth factor—are being studied for their ability to support microvessels, calm microinflammation, and nudge follicles toward healthier cycling. Microneedling may amplify these cues and upregulate Wnt signaling at the scalp, which is one reason providers layer the two in clinic workflows. Translation to durable human outcomes is still being mapped, which is why licensed clinicians set expectations carefully and measure change over time. [7–9]
What to expect
A licensed clinician begins with a focused consultation covering your hair history, patterns of thinning, current therapies, medical conditions, and goals. Established options—including minoxidil, finasteride or spironolactone when appropriate, and low-level laser therapy—are discussed alongside Hyper PRP. [10]
On procedure day expect a standard blood draw, topical anesthetic for comfort, preparation of Hyper PRP, and professional microneedling to deliver PRP evenly across targeted areas. Many people describe a prickly vibration, followed by warmth or tightness. Temporary redness or tenderness is common. Most return to normal routines the same day.
How many sessions? Expert recommendations commonly suggest series-based care. Many programs use three to five sessions spaced about a month apart, then reassess and consider individualized maintenance. The "best" schedule is still being studied, so licensed clinicians personalize timing. [11]
If you have urgent concerns after a procedure, seek immediate medical care or call emergency services.
Post-Procedure Care
For the first day, keep the scalp clean and avoid heavy sweating, hot tubs, or harsh hair products. You can usually shampoo gently after 24 hours unless your clinician advises otherwise. Expect mild soreness or tightness for a day or two. Cool compresses may help. Resume topical treatments such as minoxidil as directed; providers time these around microneedling to reduce irritation.
If you develop spreading redness, fever, significant bleeding, or other worrisome symptoms, seek medical care right away or call local emergency services.
Follow-up visits often include global photos, dermoscopy, and hair counts per square centimeter so progress is easy to see and decisions are clear.
Outcomes and Results
Some responders notice early coverage changes by about three months, with further gains by six months; others see little or no difference compared with placebo. Durability beyond several months is less certain, and maintenance needs differ. Licensed clinicians may use validated measures—like standardized hair counts and photography—to determine whether it is helping you. [1–2,4–5]
Success Stories
Patient stories can be encouraging, yet they are examples, not promises. The experiences and results shown or discussed may not occur for all patients. Simply put, individual results vary.
David Brackett | Hyper PRP™ Success Story
At 42, David Brackett felt like he was running on fumes — constant fatigue, brain fog, and a loss of drive that no amount of rest could fix. He discovered his symptoms were connected to low testosterone and poor cellular recovery. That’s when he began exploring Hyper PRP™ — a regenerative treatment that uses your own growth factors to help restore vitality, cellular function, and performance from within.
Who is a candidate?
Good candidates are generally healthy adults with androgenetic alopecia who want to add a biologic option to a whole plan program. This often includes consistent topical minoxidil, attention to scalp health, and, when appropriate, medicines such as finasteride or spironolactone. Outcome tracking helps ensure the effort is worthwhile for you. [10]
When the service may be postponed or not appropriate
- You have an active infection (fever; red, warm, or draining skin).
- You have bleeding or clotting problems (for example, hemophilia, very low platelets, or other diagnosed clotting disorders).
- You have a tendency to form blood clots or had a recent clot and are not yet stable on treatment.
- You have severe anemia (very low red blood cells).
- You have a blood cancer (such as leukemia) and are not in a stable remission under your cancer doctor’s care.
- You are pregnant or breastfeeding (for elective hair/skin services like microneedling with PRP).
- Your doctor has told you to avoid injections or blood draws for now.
Not sure? Talk with a licensed clinician. If you have one of the conditions above, ask your primary-care clinician—and the specialist who manages it (for example, a hematologist, oncologist, or OBGYN)—for guidance and clearance.
This list provides examples and is not exhaustive. Talk with a licensed provider to decide if Hyper PRP is appropriate for you. Results vary.
PRP + Microneedling + Minoxidil
Minoxidil is a vasodilator medicine used topically to help hair growth. It is a first-line therapy for androgenetic alopecia and can be paired with PRP. Meta-analysis suggests PRP plus minoxidil may outperform minoxidil alone for some patients, while microneedling with minoxidil has also outperformed minoxidil alone in randomized trials. A licensed clinician times applications around microneedling to protect the scalp. [3,6,10]
Low Level Laser Therapy
Low level laser therapy (LLLT) uses light at specific wavelengths to support cellular energy and hair cycling. A 2021 systematic review of randomized trials found LLLT improved hair density versus sham devices, and it is often used as a non-drug adjunct in home programs. A Hyper PRP provider can help you compare devices and set expectations. [13,10]
Important Safety Information — Hyper PRP™ for Hair Restoration
What this service is
Hair Restoration with Hyper PRP uses autologous platelet rich plasma (PRP) prepared from a small blood sample within a standards based Growth Factor Therapy (GFT) framework and applied to the scalp after professional microneedling by a licensed clinician. Use of PRP for androgenetic alopecia has been studied in randomized trials and pooled reviews, with signals for increased hair density in many studies and mixed findings for hair thickness. Results vary by person and protocol. [1–2,6]
Regulatory status (U.S.)
PRP preparation devices used by Hyper PRP providers are FDA cleared to prepare PRP at the point of care. PRP injections or scalp applications for hair loss are not FDA approved for this indication. Many device summaries also state that PRP has not been evaluated for clinical indications and is not indicated for delivery to the circulatory system. Licensed clinicians align care with device labeling and local regulations. [14–15]
Who may be considered [after evaluation]
Adults with androgenetic alopecia who want a non-surgical option as part of a comprehensive plan that can include first line therapies such as topical minoxidil, and when appropriate, finasteride or spironolactone. Low level laser therapy can be considered at home as an adjunct. Final candidacy is decided by you and your licensed clinician. [1–3,10,13]
Screening and focused baseline evaluation [what is typically assessed]
Before treatment, a Hyper PRP provider completes a focused review that usually covers hair loss history and pattern, family history, scalp conditions, prior treatments, goals, and comfort preferences. Safety topics that are discussed include medicines that raise bleeding risk such as anticoagulants and antiplatelets, history of easy bruising or bleeding, recent or unstable blood clots, anemia, and infection risks. This visit sets expectations and establishes how progress will be measured with photos, dermoscopy, or hair counts per square centimeter. [1–2,10–11]
How the procedure is performed [typical elements]
A small blood sample is drawn and processed to prepare Hyper PRP. The scalp is cleansed. Topical anesthetic is used for comfort. A licensed clinician performs professional microneedling across the treatment zones and applies PRP to the scalp immediately afterward. Many people return to daily activities the same day. Visit length varies by plan. [6–7]
Potential risks and side effects.
Most effects are temporary and related to microneedling and topical application. Common experiences include scalp redness, tenderness, swelling, pinpoint bleeding, or bruising. Some people notice a feeling of tightness or warmth for a day or two. Less common or rare effects include infection, scarring, pigment change, or allergic reactions to topical anesthetics. Disclose all medicines and supplements, especially blood thinners and antiplatelets. Only your prescribing clinician should adjust medicines. Seek urgent care for the red flag symptoms below. [1–2,4,6]
Who should NOT receive this service [examples].
This service is not appropriate when there is an active infection at the treatment area, critical thrombocytopenia or an uncontrolled bleeding disorder, severe anemia, known platelet function disorders, known hypersensitivity to components used for local anesthetics, or when informed consent cannot be given. Case by case judgment is needed for anticoagulation that cannot be managed safely, unstable cardiovascular disease, poorly controlled diabetes, active scalp dermatoses, or active malignancy under treatment. This list is not exhaustive. Discuss your full history with a licensed clinician. [11]
Evidence expectations (what current studies show).
Randomized trials and meta-analyses report that PRP may increase hair density compared with control over about three to six months in many studies, while effects on hair shaft diameter are mixed. Some high quality trials show little or no difference. Durability of benefit and the optimal schedule are still being studied. Results vary. [1–5]
After care and urgent concerns.
Follow your clinician’s instructions about washing and product use. Gentle shampoo is often allowed after 24 hours unless your clinician advises otherwise. Avoid heavy sweating, hot tubs, hair dye, or harsh products until you are cleared. Temporary soreness or tightness is common.
Seek immediate medical care or call emergency services if you develop rapidly worsening pain, spreading redness or warmth, fever, significant bleeding, or any symptom that worries you. [1–2]
Informed choices and alternatives.
Decisions are made jointly by you and your licensed clinician after reviewing benefits, risks, and alternatives. Alternatives and complements can include topical minoxidil, finasteride or spironolactone when appropriate, low level laser therapy, and surgical options such as hair transplantation. Your Hyper PRP provider uses shared decision making and tracks outcomes so you can see what is changing for you. [1–3,10,13]
Expectations and variability.
Benefit is not guaranteed. Protocols and biology both influence outcomes. Many people who respond notice changes by about three months with further gains by six months. Others see little change. Your clinician will set goals, measure progress with standardized photos and hair counts, and adjust the plan. [1–5,11]
How to report issues
Report suspected device or product problems or serious adverse events to FDA MedWatch. Your licensed clinician can help you submit a report. You may also file a complaint about clinical care with your state medical board. [16]
See: Expanded Candidate Information Full Important Safety Information (Coming Soon!)
Research about using PRP to support hair restoration
Supporting Scientific Evidence
What the studies generally show. Most studies looking at platelet rich plasma (PRP) for androgenetic alopecia focus on hair density, meaning the number of hairs in a set area. Recent meta analyses and reviews report that PRP may increase hair counts for many people compared with placebo or no treatment. Effects on hair thickness are less consistent, and results vary because PRP formulas and study methods differ. In plain terms, some people see fuller coverage, while others notice little or no change. [1–3]
Randomized trials. A split scalp study is a side-by-side comparison on the same person. One side gets PRP and the other side gets a comparison such as placebo or standard care. It is a way to see differences more clearly because each person serves as their own control. In these randomized trials, some people show better density on the PRP side by about three to six months, while others show little or no difference. [4–5]
How PRP and microneedling might work. Platelets carry natural signals that can support tiny blood vessels and the skin structures that house each hair follicle. PRP and microneedling have been studied for effects on blood flow and hair cycle pathways like Wnt and beta catenin. Microneedling also creates micro-channels that can trigger a gentle repair response and improve how topicals reach the scalp. These are biologic goals and confirmation in people is still evolving. [7–9]
Combining PRP, microneedling, and minoxidil. In several studies and reviews, adding PRP to a routine that already includes topical minoxidil has been associated with better density for some patients than minoxidil alone. Microneedling can also complement minoxidil by improving delivery across the scalp surface. Licensed clinicians often time minoxidil around procedure days to reduce irritation while aiming for the benefits of both. Results still vary. [3,6,10]
How care is commonly structured. In real-world practice, many licensed clinicians start with a series of visits and then reassess. A common pattern is three to five sessions before deciding on maintenance, because responses unfold over time and differ from person to person. [11]
Helpful at-home adjunct: Low-level laser therapy (LLLT). LLLT is sometimes added as a home device. Randomized trials suggest LLLT can support density for some users and may fit alongside clinic-based care. [13]
Bottom line. PRP has been studied for pattern hair loss and may help some people increase hair density, especially when used as part of a thoughtful plan. Outcomes differ, and expectations should be personalized. [1–5]
Frequently Asked Questions
Alternatives and Related Services
- FUE Hair Transplanation
- Microneedling
Citations and References
Grouped by subject
Hair restoration: meta-analyses and combination evidence
1. Kieling L, Emmel V, Sølvsten H, Lachiana M. Is autologous plateletrich plasma capable of increasing hair density in androgenetic alopecia? Int J Dermatol. 2024. PMID: 39013743.
2. Li M, Sun Y, Xu P, et al. Effectiveness of plateletrich plasma in androgenic alopecia: a metaanalysis. Aesthetic Plast Surg. 2023;47:ePub. PMID: 373497767.
3. Yao J, Zhu L, Pan M, Shen L, Tang Y, et al. The additive value of PRP to topical minoxidil in androgenetic alopecia: systematic review and metaanalysis. PLoS One. 2024;19(8):e0308986. doi:10.1371/journal.pone.0308986.
2. Randomized trials—PRP for androgenetic alopecia
4. Shapiro J, Ho A, Sukhdeo K, Yin L, Lo Sicco K. PRP for androgenetic alopecia: randomized, placebocontrolled splitscalp trial. J Am Acad Dermatol. 2020;83(5):1298-1303. PMID: 32653577.
5. Alves R, Grimalt R. Plateletrich plasma for androgenetic alopecia: randomized, doubleblind, placebocontrolled halfhead study. Dermatol Surg. 2016;44(1):126-130. PMID: 28562433.
3. Microneedling and mechanisms
6. Dhurat R, Sukesh M, Avhad G, Dandale A, Pal A, Pund P. Microneedling in androgenetic alopecia: randomized evaluatorblinded study vs minoxidil alone. Int J Trichology. 2013;5(1):6-11. doi:10.4103/0974-7753.114700.
7. Jha AK, Udayan UK, Kedia SK. Androgenetic alopecia and microneedling: every needling counts? J Am Acad Dermatol. 2019;81(6):e153-e154. doi:10.1016/j.jaad.2019.07.082.
8. Abdin R, Dastgheib SA, Mahmoudi H, et al. PRP in androgenetic alopecia: targeting dysregulated molecular pathways. Front Med. 2022;9:843127. doi:10.3389/fmed.2022.843127.
9. PozoPérez L, Fronza M, Paus R. Regenerative strategies and signaling in androgenetic alopecia. Stem Cell Res Ther. 2024;15:226. doi:10.1186/s13287-024-03801-5.
4. Practice guidance and recommendations
10. Devjani S, Mysore V. Androgenetic alopecia: therapy update. Drugs. 2023;83(12):1061-1084. doi:10.1007/s40265-023-01880-x.
11. Sharma A, Kaur T, Sandhu S, et al. Plateletrich plasma in androgenetic alopecia: expert recommendations. Indian Dermatol Online J. 2021;12(Suppl 1):S61-S73. doi:10.4103/idoj.IDOJ_657_20.
12. Kaiser M, Chatzigeorgiou O, et al. Treatment of androgenetic alopecia: current guidance and unmet needs. Clin Cosmet Investig Dermatol. 2023;16:1165-1183.
5. Adjuncts (home light/laser devices)
13. Lueangarun S, Visutjindaporn P, Parcharoen Y, et al. FDAcleared homeuse lowlevel light/laser therapy devices for pattern hair loss: systematic review and metaanalysis of randomized trials. J Clin Aesthet Dermatol. 2021 Nov. PMID: 34980962.
6. Regulatory and reporting (U.S.)
14. U.S. FDA. 510(k) Summary—FG001 PlateletRich Plasma Device (K241083). 2024. Notes: not evaluated for clinical indications; not indicated for intravascular delivery.
15. U.S. FDA. 510(k) Summary—GPS III Separator device with ACDA (K230844). 2023.
16. U.S. FDA. MedWatch—Reporting serious problems to FDA. Accessed 2025.
Emergency or urgent concerns: If worrisome symptoms appear after a procedure—such as rapidly worsening pain, spreading redness, fever, significant bleeding, or any symptom that concerns you— seek immediate medical care or call local emergency services.
Important Reminder: This information is educational and does not replace medical advice. Talk with a qualified clinician to see whether Hyper PRP and any related services are appropriate for you, to review alternatives, and to understand potential benefits and risks.
Important Notice
Results are not guaranteed; individual results vary. Some uses—including ED—are investigational. Hyper PRP is prepared using FDA-cleared devices for PRP preparation; PRP injections for specific conditions are not FDA-approved and are not indicated for intravascular delivery. This site is informational and does not establish a doctor-patient relationship. Do not submit sensitive health information through web forms. If this is an emergency, call 911.